Skip to main content Skip to main menu
UF Health University of Florida
Center for Natural Products, Drug Discovery and Development (CNPD3) College of Pharmacy

Members

Director

Hendrik Luesch

Hendrik Luesch Ph.D.

Professor; The Debbie And Sylvia DeSantis Chair In Natural Products Drug Discovery And Development; Director of the Center for Natural Products, Drug Discovery and Development
Phone: (352) 273-7738
Email: luesch@ufl.edu
Mailing Address:
Physical Address:
Publications:
Patents:
  • Issued August 2023
    Macrocyclic Therapeutic Agents, Methods of Manufacture, and Methods of Treatment
    #11,718,646
  • Published April 2023
    Macrocyclic Compounds and Methods of Treatment
    #US-2024-0002396-A1
  • Issued June 2022
    Apratyramide Therapeutic Agents and Methods of Treatment
    #11,358,989
  • Issued February 2022
    Analogs of Yohimbine and Uses Thereof
    #11,242,331
  • Published January 2022
    Discovery, Total Synthesis, and Bioactivity of Doscadenamides
    #US23-0242482-A9
  • Issued September 2021
    Analogs of Vincamine and Uses Thereof
    #11,130,764
  • Published April 2019
    Engineered Streptomyces Albus Strains
    #US-2021-0163964-A1
  • Published December 2018
    Seaweed Extracts, Isolated Compounds, and Methods of Treatment
    #US-2021-0161980-A1
  • Issued July 2018
    Seaweed Extracts, Unsaturated Fatty Acids, and Methods of Treatment
    #10,010,569
  • Issued November 2017
    Macrocyclic Compounds and Methods of Treatment
    #9,815,852
  • Issued August 2017
    Seaweed Extracts, Unsaturated Aldehydes, and Methods of Treatment
    #9,730,970
  • Issued November 2016
    Combination Compositions and Methods of Treatment
    #9,492,434
  • Published August 2016
    Macrocyclic Therapeutic Agents, Methods of Manufacture, and Methods of Treatment
    #US-2017-0057996
  • Issued November 2015
    Macrocyclic Compounds and Methods of Treatment
    #9,181,304
  • Published November 2015
    Potent New Synthetic Apratoxins
    #US-2016-0060299-A1
  • Published October 2015
    Macrocyclic Compounds and Methods of Treatment
    #US 2016/0106720
  • Issued June 2015
    Macrocyclic Antiproliferation Agents and Methods of Treatment
    #9,051,350
  • Issued May 2015
    Macrocyclic Compounds and Methods of Treatment (DIV of UF#12606)
    #9,023,875
  • Published August 2014
    Macrocyclic Compounds
    #US2015-0038404 A1
  • Issued June 2014
    Methods of Preparation of Macrocyclic Compounds
    #8,759,512
  • Issued October 2013
    Structure and Protease Activity of Grassystatins
    #8,569,245
  • Issued January 2013
    Macrocyclic Compounds and Methods of Treatment (DIV of 12606)
    #8,357,708
  • Published November 2012
    Macrocyclic Compounds and Methods of Treatment
    #US2013-0281497 A1
  • Issued March 2012
    Macrocyclic Compounds and Methods of Treatment
    #8,129,418
  • Published May 2011
    Apratoxin Therapetuic Agents: Mechanism and Methods of Treatment
    #US 2011-0294720 A1
  • Published December 2010
    Macrocyclic Compounds and Methods of Treatment (New App.)
    #2011-0123644 A1
  • Published March 2010
    Macrocyclic Compounds, Protease Inhibition, and Methods of Treatment
    #US2011-0124569A1
Education:
  • 2002-2005
    Postdoctoral Fellow
    The Scripps Research Institute
  • 2002
    Ph.D.
    University of Hawaii at Manoa
  • 1997
    Diplom in Chemistry
    University of Siegen
Full Profile

Associate Director for Drug Design

Chenglong Li

Chenglong Li Ph.D.

Chair of Medicinal Chemistry and the Nicholas Bodor Professor in Drug Discovery
Phone: (352) 294-8510
Email: lic@ufl.edu
Mailing Address:
Physical Address:
Publications:
Patents:
  • Published February 2019
    IL-6 Inhibitors and Methods of Treatment
    #US-2021-0206718-A1
Education:
  • 2000
    Ph.D.
    Cornell University
  • 1988
    M.Sc.
    Beijing University
  • 1985
    B.Sc.
    Beijing University
Full Profile

Associate Director for Synthetic Biology

Yousong Ding

Yousong Ding Ph.D.

Professor
Phone: (352) 273-7742
Email: dingyous@ufl.edu
Mailing Address:
Physical Address:
Publications:
Patents:
  • Issued January 2024
    Modified Bacteria For Production of Nitroaromatics
    #11,879,144
  • Issued May 2023
    Methods of Thaxtomin Production and Engineered Non-Native Steptomyces with Increased Thaxtomin Production
    #11,655,477
  • Issued February 2023
    Modified Bacteria For Production of Nitroaromatics
    #11,591,627
  • Published October 2022
    Fungal Glycan Binding Protein Which Possesses Antiviral and Anticancer Activity
    #US-2023-0272019-A1
  • Published June 2022
    Compositions and Methods for Transgenic Crops Resistant to Thaxtomins
    #US-2023-0348929-A1
  • Issued June 2022
    Cyanobacterial Hosts and Methods for Producing Chemicals
    #11,352,601
  • Issued August 2021
    Highly Active Self-Sufficient Nitration Biocatalysts
    #11,078,467
  • Published April 2020
    Recombinant Glycan Binding Proteins
    #US2022/0227820A1
  • Issued February 2020
    Artificial Self-Sufficient Cytochrome P450S
    #10,550,079
  • Issued November 2018
    Artificial Self-Sufficient Cytochrome P450S
    #10,138,205
  • Published July 2018
    A Fungal Glycan Binding Protein Possesses Antiviral and Anticancer Activity
    #US-2021-0094988-A1
Education:
  • 2012-2013
    Principal Scientist
    Bioprocess Development Group, Pfizer
  • 2010-2012
    Postdoctoral Fellow
    California Institute of Technology
  • 2010
    Ph.D.
    University of Michigan, Ann Arbor
  • 2004
    M.S.
    University of Nebraska
  • 2000
    B.S.
    Peking University
Full Profile

Assistant Director

Ranjala Ratnayake

Ranjala Ratnayake Ph.D.

Research Associate Professor
Phone: (352) 627-9220
Email: rratnayake@ufl.edu
Mailing Address:
Physical Address:
Publications:
Patents:
  • Issued August 2017
    Seaweed Extracts, Unsaturated Aldehydes, and Methods of Treatment
    #9,730,970
Education:
  • 2007
    Ph.D.
    University of Queensland
  • 2005
    M.Phil.
    The Open University of Sri Lanka
  • 2001
    B.Sc.
    The Open University of Sri Lanka
Full Profile

Core Directors/Core Leaders

Members

Department of Medicinal Chemistry

Department of Pharmacodynamics

Department of Pharmaceutics

Department of Chemistry

Department of Biology

Department of Medicine

Department of Pharmacology & Therapeutics

Department of Microbiology and Cell Sciences

Department of Statistics